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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK2
All Species:
33.94
Human Site:
S450
Identified Species:
74.67
UniProt:
Q86UE8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UE8
NP_001106178.1
772
87661
S450
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Chimpanzee
Pan troglodytes
XP_523598
848
95816
S526
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Rhesus Macaque
Macaca mulatta
XP_001107302
907
100501
S585
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Dog
Lupus familis
XP_548038
918
102784
S596
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Cat
Felis silvestris
Mouse
Mus musculus
O55047
718
82242
S396
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
S396
R
I
N
N
E
D
N
S
Q
F
K
D
H
P
T
Chicken
Gallus gallus
XP_418070
750
85456
S428
R
I
H
N
E
D
N
S
Q
F
K
D
H
P
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECX4
697
79286
T383
S
Q
F
K
D
H
P
T
L
N
D
R
Y
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
S457
R
I
H
N
E
D
Q
S
R
F
N
S
H
P
V
Nematode Worm
Caenorhab. elegans
P34314
965
109255
S639
R
A
S
N
E
S
A
S
Q
F
N
D
H
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
R374
E
E
A
V
L
R
E
R
E
R
Y
T
L
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
82.3
81.2
N.A.
92.4
N.A.
N.A.
68.6
94.1
N.A.
77.9
N.A.
N.A.
47.9
36.5
N.A.
Protein Similarity:
100
88.3
83
81.3
N.A.
92.7
N.A.
N.A.
77.7
95.8
N.A.
83.9
N.A.
N.A.
63.4
50.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
93.3
100
N.A.
0
N.A.
N.A.
66.6
53.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
20
N.A.
N.A.
73.3
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
73
0
0
0
0
10
73
0
0
0
% D
% Glu:
10
10
0
0
82
0
10
0
10
0
0
0
0
10
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
82
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
64
0
0
10
0
0
0
0
0
0
82
0
0
% H
% Ile:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
64
0
0
0
10
% K
% Leu:
0
0
0
0
10
0
0
0
10
0
0
0
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
82
0
0
64
0
0
10
19
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
73
0
% P
% Gln:
0
10
0
0
0
0
10
0
73
0
0
0
0
0
0
% Q
% Arg:
82
0
0
0
0
10
0
10
10
10
0
10
0
10
0
% R
% Ser:
10
0
10
0
0
10
0
82
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
64
% T
% Val:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _